Macbook Pro (Early 2015) bluetooth issues after waking from sleep

Just got a new MacBook Pro (Retina, 13-inch, Early 2015), but there are several problems with bluetooth. Most of them occur when waking from sleep:

1. Sometimes the bluetooth icon shows "Not available". The bluetooth hardware then also doesn't show up in System Information.
2. Sometimes the bluetooth icon and preferences indicate that it's turned off, but nothing happens when I click "Turn on".

The only remedy for these problems is to completely restart the computer. In some cases, it hangs on the 'shutdown loading spinner', and then restarts with a kernel panic message. I attached the latest panic log below.

I tried trashing the bluetooth preferences and resetting the SMC, but that doesn't seem to permanently fix the problems.

Could this be a hardware issue?

*** Panic Report ***
panic(cpu 1 caller 0xffffff800edd6bba): Kernel trap at 0xffffff7f900ed402, type 14=page fault, registers:
CR0: 0x000000008001003b, CR2: 0x00000000000000bf, CR3: 0x0000000011f99000, CR4: 0x00000000003627e0
RAX: 0x0000000000000000, RBX: 0xffffff802e913300, RCX: 0xfffffffe803b8924, RDX: 0x0000000000000001
RSP: 0xffffff81f7513b20, RBP: 0xffffff81f7513b30, RSI: 0xffffff802f0dd000, RDI: 0xffffff802e913300
R8:  0xffffff802d794000, R9:  0x0000000000000001, R10: 0x0000000000000000, R11: 0x0000000000000028
R12: 0xffffff802ec10a00, R13: 0xffffff7f900a422c, R14: 0x0000000000000000, R15: 0xffffff802f0dd000
RFL: 0x0000000000010286, RIP: 0xffffff7f900ed402, CS:  0x0000000000000008, SS:  0x0000000000000010
Fault CR2: 0x00000000000000bf, Error code: 0x0000000000000000, Fault CPU: 0x1, PL: 0

Backtrace (CPU 1), Frame : Return Address
0xffffff81f75137b0 : 0xffffff800ece5307 
0xffffff81f7513830 : 0xffffff800edd6bba 
0xffffff81f7513a10 : 0xffffff800edf4313 
0xffffff81f7513a30 : 0xffffff7f900ed402 
0xffffff81f7513b30 : 0xffffff7f9019fadb 
0xffffff81f7513b70 : 0xffffff7f9019bf24 
0xffffff81f7513b90 : 0xffffff800f2b8538 
0xffffff81f7513c00 : 0xffffff7f9019beab 
0xffffff81f7513c40 : 0xffffff7f901c7e14 
0xffffff81f7513d20 : 0xffffff7f901ad013 
0xffffff81f7513e70 : 0xffffff7f901acf38 
0xffffff81f7513f30 : 0xffffff7f900d1117 
0xffffff81f7513f50 : 0xffffff7f900d10c6 
0xffffff81f7513f70 : 0xffffff7f900d113c 
0xffffff81f7513f90 : 0xffffff7f900d123e 
0xffffff81f7513fb0 : 0xffffff800edd15d7 
      Kernel Extensions in backtrace:
         com.apple.iokit.IOBluetoothFamily(4.4.2f1)[B3BAA668-8A2E-35FC-9683-5D3C87498A43]@0xffffff7f900a0000->0xffffff7f9015cfff
            dependency: com.apple.iokit.IOReportFamily(31)[00ECF188-29A2-3C48-B4DD-B155077F7B3C]@0xffffff7f8ff21000
         com.apple.iokit.IOBluetoothHostControllerUSBTransport(4.4.2f1)[1E8E8B9C-0CFA-3666-8818-36296141B28C]@0xffffff7f9019b000->0xffffff7f901c4fff
            dependency: com.apple.iokit.IOBluetoothFamily(4.4.2f1)[B3BAA668-8A2E-35FC-9683-5D3C87498A43]@0xffffff7f900a0000
            dependency: com.apple.iokit.IOACPIFamily(1.4)[CBAE26D8-0ACB-3C1F-8347-FDCA67EC40B3]@0xffffff7f8fc15000
            dependency: com.apple.iokit.IOPCIFamily(2.9)[8E5F549E-0055-3C0E-93F8-E872A048E31B]@0xffffff7f8f52d000
            dependency: com.apple.iokit.IOUSBHostFamily(1.0.1)[CB073B0F-F3E0-37BD-8091-390367BEDAB0]@0xffffff7f8fa39000
         com.apple.iokit.BroadcomBluetoothHostControllerUSBTransport(4.4.2f1)[0DFBD99C-2B34-3A85-A2DB-FF916490A8CE]@0xffffff7f901c5000->0xffffff7f901cffff
            dependency: com.apple.iokit.IOBluetoothHostControllerUSBTransport(4.4.2f1)[1E8E8B9C-0CFA-3666-8818-36296141B28C]@0xffffff7f9019b000
            dependency: com.apple.iokit.IOBluetoothFamily(4.4.2f1)[B3BAA668-8A2E-35FC-9683-5D3C87498A43]@0xffffff7f900a0000
            dependency: com.apple.iokit.IOACPIFamily(1.4)[CBAE26D8-0ACB-3C1F-8347-FDCA67EC40B3]@0xffffff7f8fc15000
            dependency: com.apple.iokit.IOPCIFamily(2.9)[8E5F549E-0055-3C0E-93F8-E872A048E31B]@0xffffff7f8f52d000
            dependency: com.apple.iokit.IOUSBHostFamily(1.0.1)[CB073B0F-F3E0-37BD-8091-390367BEDAB0]@0xffffff7f8fa39000

BSD process name corresponding to current thread: kernel_task

Mac OS version:
15B42

Kernel version:
Darwin Kernel Version 15.0.0: Sat Sep 19 15:53:46 PDT 2015; root:xnu-3247.10.11~1/RELEASE_X86_64
Kernel UUID: AB5FC1B4-12E7-311E-8E6F-9023985D8C1D
Kernel slide:     0x000000000ea00000
Kernel text base: 0xffffff800ec00000
__HIB  text base: 0xffffff800eb00000
System model name: MacBookPro12,1 (Mac-E43C1C25D4880AD6)

System uptime in nanoseconds: 81497173879650
last loaded kext at 81351682643855: com.apple.driver.AppleXsanScheme    3 (addr 0xffffff7f918d0000, size 32768)
last unloaded kext at 58246112314891: com.apple.driver.AppleXsanScheme  3 (addr 0xffffff7f918c7000, size 32768)
loaded kexts:
org.virtualbox.kext.VBoxNetAdp  5.0.0
org.virtualbox.kext.VBoxNetFlt  5.0.0
org.virtualbox.kext.VBoxUSB 5.0.0
org.virtualbox.kext.VBoxDrv 5.0.0
com.apple.iokit.SCSITaskUserClient  3.7.7
com.apple.iokit.IOBluetoothUSBDFU   4.4.2f1
com.apple.driver.AppleUSBStorageCoexistentDriver    3.7.1
com.apple.filesystems.smbfs 3.0.0
com.apple.driver.AudioAUUC  1.70
com.apple.driver.AGPM   110.20.21
com.apple.driver.ApplePlatformEnabler   2.5.1d0
com.apple.driver.X86PlatformShim    1.0.0
com.apple.filesystems.autofs    3.0
com.apple.driver.AppleOSXWatchdog   1
com.apple.driver.AppleGraphicsDevicePolicy  3.7.7
com.apple.driver.AppleUpstreamUserClient    3.6.1
com.apple.driver.AppleHDA   272.50.31
com.apple.driver.pmtelemetry    1
com.apple.iokit.IOUserEthernet  1.0.1
com.apple.iokit.IOBluetoothSerialManager    4.4.2f1
com.apple.Dont_Steal_Mac_OS_X   7.0.0
com.apple.driver.AppleBacklight 170.8.1
com.apple.driver.AppleLPC   3.1
com.apple.driver.AppleHV    1
com.apple.driver.AppleThunderboltIP 3.0.8
com.apple.iokit.BroadcomBluetoothHostControllerUSBTransport 4.4.2f1
com.apple.driver.AppleIntelBDWGraphics  10.1.0
com.apple.driver.AppleMCCSControl   1.2.13
com.apple.driver.AppleCameraInterface   5.41.0
com.apple.driver.AppleSMCLMU    208
com.apple.driver.AppleIntelSlowAdaptiveClocking 4.0.0
com.apple.driver.AppleIntelBDWGraphicsFramebuffer   10.1.0
com.apple.driver.AppleUSBCardReader 3.7.1
com.apple.AppleFSCompression.AppleFSCompressionTypeDataless 1.0.0d1
com.apple.AppleFSCompression.AppleFSCompressionTypeZlib 1.0.0
com.apple.BootCache 37
com.apple.iokit.IOAHCIBlockStorage  2.8.0
com.apple.driver.AppleAHCIPort  3.1.5
com.apple.driver.AppleTopCaseHIDEventDriver 86
com.apple.driver.AirPort.Brcm4360   1010.14.1a4
com.apple.driver.AppleHPET  1.8
com.apple.driver.AppleSmartBatteryManager   161.0.0
com.apple.driver.AppleACPIButtons   4.0
com.apple.driver.AppleRTC   2.0
com.apple.driver.AppleSMBIOS    2.1
com.apple.driver.AppleACPIEC    4.0
com.apple.driver.AppleAPIC  1.7
com.apple.nke.applicationfirewall   163
com.apple.security.quarantine   3
com.apple.security.TMSafetyNet  8
com.apple.driver.AppleXsanScheme    3
com.apple.iokit.IOUSBMassStorageClass   4.0.0
com.apple.driver.AppleBluetoothHIDKeyboard  181
com.apple.driver.IOBluetoothHIDDriver   4.4.2f1
com.apple.driver.usb.AppleUSBHub    1.0.1
com.apple.driver.usb.AppleUSBHostCompositeDevice    1.0.1
com.apple.iokit.IOUSBUserClient 900.4.1
com.apple.kext.triggers 1.0
com.apple.driver.DspFuncLib 272.50.31
com.apple.kext.OSvKernDSPLib    525
com.apple.driver.AppleGraphicsControl   3.11.33b1
com.apple.driver.CoreCaptureResponder   1
com.apple.driver.AppleBacklightExpert   1.1.0
com.apple.iokit.IOBluetoothHostControllerUSBTransport   4.4.2f1
com.apple.iokit.IOBluetoothFamily   4.4.2f1
com.apple.iokit.IOSurface   108.0.1
com.apple.driver.AppleHDAController 272.50.31
com.apple.iokit.IOHDAFamily 272.50.31
com.apple.iokit.IOAudioFamily   204.1
com.apple.vecLib.kext   1.2.0
com.apple.driver.AppleSMBusController   1.0.14d1
com.apple.driver.X86PlatformPlugin  1.0.0
com.apple.driver.IOPlatformPluginFamily 6.0.0d7
com.apple.iokit.IOSerialFamily  11
com.apple.driver.AppleSMC   3.1.9
com.apple.iokit.IOSlowAdaptiveClockingFamily    1.0.0
com.apple.iokit.IONDRVSupport   2.4.1
com.apple.AppleGraphicsDeviceControl    3.11.33b1
com.apple.iokit.IOAcceleratorFamily2    203.10
com.apple.iokit.IOGraphicsFamily    2.4.1
com.apple.iokit.IOSCSIBlockCommandsDevice   3.7.7
com.apple.iokit.IOUSBMassStorageDriver  1.0.0
com.apple.iokit.IOSCSIArchitectureModelFamily   3.7.7
com.apple.driver.usb.IOUSBHostHIDDevice 1.0.1
com.apple.driver.CoreStorage    517
com.apple.iokit.IOAHCIFamily    2.8.0
com.apple.driver.AppleThunderboltDPInAdapter    4.1.2
com.apple.driver.AppleThunderboltDPAdapterFamily    4.1.2
com.apple.driver.AppleThunderboltPCIDownAdapter 2.0.2
com.apple.driver.AppleHIDKeyboard   181
com.apple.driver.AppleMultitouchDriver  304.9
com.apple.driver.AppleHIDTransport  5
com.apple.driver.AppleHSSPIHIDDriver    41.6
com.apple.driver.AppleThunderboltNHI    4.0.4
com.apple.iokit.IOThunderboltFamily 5.0.6
com.apple.iokit.IO80211Family   1101.24
com.apple.driver.mDNSOffloadUserClient  1.0.1b8
com.apple.iokit.IONetworkingFamily  3.2
com.apple.driver.corecapture    1.0.4
com.apple.driver.AppleHSSPISupport  41.6
com.apple.driver.AppleIntelLpssSpiController    2.0.57
com.apple.driver.AppleIntelLpssGspi 2.0.57
com.apple.driver.usb.AppleUSBXHCIPCI    1.0.1
com.apple.driver.usb.AppleUSBXHCI   1.0.1
com.apple.driver.AppleIntelLpssDmac 2.0.57
com.apple.iokit.IOUSBFamily 900.4.1
com.apple.iokit.IOUSBHostFamily 1.0.1
com.apple.driver.AppleUSBHostMergeProperties    1.0.1
com.apple.driver.AppleEFINVRAM  2.0
com.apple.driver.AppleEFIRuntime    2.0
com.apple.iokit.IOHIDFamily 2.0.0
com.apple.iokit.IOSMBusFamily   1.1
com.apple.security.sandbox  300.0
com.apple.kext.AppleMatch   1.0.0d1
com.apple.driver.AppleKeyStore  2
com.apple.driver.AppleMobileFileIntegrity   1.0.5
com.apple.driver.AppleCredentialManager 1.0
com.apple.driver.DiskImages 415
com.apple.iokit.IOStorageFamily 2.1
com.apple.iokit.IOReportFamily  31
com.apple.driver.AppleFDEKeyStore   28.30
com.apple.driver.AppleACPIPlatform  4.0
com.apple.iokit.IOPCIFamily 2.9
com.apple.iokit.IOACPIFamily    1.4
com.apple.kec.Libm  1
com.apple.kec.pthread   1
com.apple.kec.corecrypto    1.0
Model: MacBookPro12,1, BootROM MBP121.0167.B14, 2 processors, Intel Core i5, 2,9 GHz, 16 GB, SMC 2.28f7
Graphics: Intel Iris Graphics 6100, Intel Iris Graphics 6100, Built-In
Memory Module: BANK 0/DIMM0, 8 GB, DDR3, 1867 MHz, 0x02FE, 0x4544464232333241314D412D4A442D460000
Memory Module: BANK 1/DIMM0, 8 GB, DDR3, 1867 MHz, 0x02FE, 0x4544464232333241314D412D4A442D460000
AirPort: spairport_wireless_card_type_airport_extreme (0x14E4, 0x133), Broadcom BCM43xx 1.0 (7.21.94.29.1a4)
Bluetooth: Version 4.4.2f1 16391, 3 services, 27 devices, 1 incoming serial ports
Network Service: Wi-Fi, AirPort, en0
Serial ATA Device: APPLE SSD SM0512G, 500,28 GB
USB Device: USB 3.0 Bus
USB Device: Bluetooth USB Host Controller
USB Device: Hub
USB Device: USB-PS/2 Optical Mouse
USB Device: Ext HDD 1021
Thunderbolt Bus: MacBook Pro, Apple Inc., 27.1