I am having issues with 12.10.
The mouse seems to work on some parts of Ubuntu and not others. for example, I can open apps using the left home bar thing, and if they are full-screen, with the button, I can navigate through folders, but if I open a web browser, I cannot click on anything in the browser, though I can use the keyboard and tab around. If the web browser is also not full screen, and the close/min/max buttons are on the top right, in black, I cannot use them.
when this is the case, the mouse is not at all frozen. I can move the cursor freely, open new apps, navigate through Ubuntu, only cannot click in any open apps with the mouse.
There is nothing wrong with the mouse, as it works great on Windows, and I have tried both my RAT 7 and performance MX wireless mouses, to the same effect.
My hardware: P8Z77-V_LX mobo, i5 3570k, 16GB RAM (DDR3 1600Mhz), booted off Patriot Pyro SSD 120GB, integrated graphics 4000 (yeah, yeah, I'm getting something when I can afford it. built for upgradeability)
DualBoot Windows 7 Pro & Ubuntu 12.10
Best Answer
I've experienced the same, but it happened when a game froze and I rebooted from the terminal.
The manual workaround is to switch to the text console with Ctrl+Alt+F1 and go back to X11 with Ctrl+Alt+F7. Someone else's answer, but it works for me.