Windows – Manually remove Microsoft Visual Studio 2010 Tools for Office Runtime (x86)

I was able to find this with a quick google search (link):

2.4.11.2 Debugger start fails if the IntelliTrace recordings directory is Read-Only

By default, IntelliTrace files are located in the "%ProgramData%\Microsoft Visual
Studio\10.0\TraceDebugging\" directory.  If this directory is made read-only, or the 
directory is changed to a read-only location, an uncaught exception gets raised to the 
user.  "Error while trying to run project: Uncaught exception thrown by method called 
through Reflection."

To resolve this issue:

* Option 1: Modify the permissions of the directory to be writable. 
* Option 2: Change the directory where IntelliTrace recordings are stored.
      o In Visual Studio, open the Options dialog box.
      o Expand the IntelliTrace item in the left pane of the dialog box.
      o Click the Advanced item under IntelliTrace.
      o Change the IntelliTrace recordings directory to one that is not read-only.
      o Click OK.

Ok, sadly the best I could find was to completely reformat and reinstall. What I'd done was corrupt my user profile (public folders, etc) when I tried to move them off of the C drive to make more room on the solid state.

Not a very good plan, all in all and that messed up a whole lot of things.

Still can't pinpoint the exact cause, but there's the solution. Reformat and reinstall.