I have a mid-2012 MacBook Pro Retina, and am using QuietComfort20 headphones that previously used to work.
Now, after a clean install of OS X Yosemite, I'm unable to use the headphones, no audio comes through them at all.
When I adjust the volume use F11 or F12 I get the following
Best Answer
Seems that the Audio Output selector was "Parallels Access Audio". When I used parallels access apparently the default output was changed, and not reverted.