If you don't mind typing directly above the pane border (which you have to do anyway for any panel that doesn't touch the status line), you can force tmux to use a smaller window:
set force-height <single_window_height - 1>
However this only is a per-window setting and acts as maximum height limit hence it won't do what you want when you change your containing terminal dimesions.
Best Answer
You can call a shell script from tmux's status line, specifying your required interface like so:
And place this script, speed1, in your $PATH:
1. Can't remember where I found this...