It seems a very common issue and I'm stunned reading that WON'T FIX!
Briefly, I noted that global shortcut keys (such as Ctrl+Space I use to call my favourite launcher) doesn't work when focus is on certain applications windows (gnome-terminal or gedit, for example) but only when I'm running Wayland.
Moreover, if I use xfce4-panel and the window buttons element, the button won't appear for the same apps.
With other apps (chromium, thunderbird, synapse, for example) both issues are not presenting.
Best Answer
And what do you want to say?
Bug with global shortcuts is known on launchpad as bug 1244090.
Keyboard bug for Ctrl+Shift+c, Ctrl+Shift+v and so on is reported to launchpad as bug 1245473.
Also there is another problem with non-latin shortcuts - it is known as launchpad bug 1226962.
Also users want to set Alt+Shift or Ctrl+ Shift as keyboard layout switcher as in launchpad bug 1218322 but can do this only from GNOME Tweaks.
Myself I found only one resolution - I'll stay on Ubuntu 16.04 LTS MATE until 2021 year (really 2019 because it's Ubuntu flavor).