This was not an issue with Ubuntu 18.04.
When on Ubuntu 19.04 which I just installed fresh I noticed it even already using the LiveCD.
I have only found this problem using Microsoft Standard Optical Mouse.
A generic cheap USB mouse had no trouble scrolling as expected.
I've tried rebooting and other USB 2.0 and 3.0 ports.
I also experienced the same issue on the latest Fedora 30 so maybe it could be related to kernel modules ?
$ uname -a
Linux 5.0.0-13-generic #14-Ubuntu SMP Mon Apr 15 14:59:14 UTC 2019 x86_64 x86_64 x86_64 GNU/Linux
$ xinput list
⎡ Virtual core pointer id=2 [master pointer (3)]
⎜ ↳ Virtual core XTEST pointer id=4 [slave pointer (2)]
⎜ ↳ Microsoft Microsoft Wireless Optical Desktop® 2.10 id=11 [slave pointer (2)]
⎣ Virtual core keyboard id=3 [master keyboard (2)]
↳ Virtual core XTEST keyboard id=5 [slave keyboard (3)]
↳ Power Button id=6 [slave keyboard (3)]
↳ Video Bus id=7 [slave keyboard (3)]
↳ Power Button id=8 [slave keyboard (3)]
↳ Sleep Button id=9 [slave keyboard (3)]
↳ Microsoft Microsoft Wireless Optical Desktop® 2.10 id=10 [slave keyboard (3)]
↳ Microsoft Microsoft Wireless Optical Desktop® 2.10 id=12 [slave keyboard (3)]
$ xinput list-props 11
Device 'Microsoft Microsoft Wireless Optical Desktop® 2.10':
Device Enabled (163): 1
Coordinate Transformation Matrix (165): 1.000000, 0.000000, 0.000000, 0.000000, 1.000000, 0.000000, 0.000000, 0.000000, 1.000000
libinput Natural Scrolling Enabled (300): 0
libinput Natural Scrolling Enabled Default (301): 0
libinput Scroll Methods Available (302): 0, 0, 1
libinput Scroll Method Enabled (303): 0, 0, 0
libinput Scroll Method Enabled Default (304): 0, 0, 0
libinput Button Scrolling Button (305): 2
libinput Button Scrolling Button Default (306): 2
libinput Middle Emulation Enabled (307): 0
libinput Middle Emulation Enabled Default (308): 0
libinput Accel Speed (309): 0.000000
libinput Accel Speed Default (310): 0.000000
libinput Accel Profiles Available (311): 1, 1
libinput Accel Profile Enabled (312): 1, 0
libinput Accel Profile Enabled Default (313): 1, 0
libinput Left Handed Enabled (314): 0
libinput Left Handed Enabled Default (315): 0
libinput Send Events Modes Available (285): 1, 0
libinput Send Events Mode Enabled (286): 0, 0
libinput Send Events Mode Enabled Default (287): 0, 0
Device Node (288): "/dev/input/event5"
Device Product ID (289): 1118, 157
libinput Drag Lock Buttons (316): <no items>
libinput Horizontal Scroll Enabled (317): 1
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