Ubuntu – How to make xinput settings persist after devices are unplugged, replugged, and after shutdown, restart, etc

You can use xinput to set the sensitivities/accels for the mice.

$ xinput list
⎡ Virtual core pointer                      id=2    [master pointer  (3)]
⎜   ↳ Virtual core XTEST pointer                id=4    [slave  pointer  (2)]
⎜   ↳ Logitech USB-PS/2 Optical Mouse           id=8    [slave  pointer  (2)]
⎜   ↳ Microsoft Microsoft® Nano Transceiver v2.0    id=10   [slave  pointer  (2)]
⎜   ↳ Microsoft Microsoft® Nano Transceiver v2.0    id=11   [slave  pointer  (2)]
⎜   ↳ Macintosh mouse button emulation          id=13   [slave  pointer  (2)]
⎣ Virtual core keyboard                     id=3    [master keyboard (2)]
    ↳ Virtual core XTEST keyboard               id=5    [slave  keyboard (3)]
    ↳ Power Button                              id=6    [slave  keyboard (3)]
    ↳ Power Button                              id=7    [slave  keyboard (3)]
    ↳ Microsoft Microsoft® Nano Transceiver v2.0    id=9    [slave  keyboard (3)]
    ↳ AT Translated Set 2 keyboard              id=12   [slave  keyboard (3)]

From that output take the numeric id of the mice. I'll provide an example for my Logitech mouse. For multiple mice rinse and repeat.

So for my logitech I will use xinput get-feedbacks <device name> and xinput set-ptr-feedback <device name> <threshold> <num> <denom>

$ xinput get-feedbacks 8
1 feedback class
PtrFeedbackClass id=0
    accelNum is 3
    accelDenom is 10
    threshold is 4

The accel is set as a fraction so you need to set the nom and denom for it:

$ xinput set-ptr-feedback 8 4 3 1
$ xinput get-feedbacks 8
1 feedback class
PtrFeedbackClass id=0
    accelNum is 3
    accelDenom is 1
    threshold is 4

I was having that problem with one laptop repeatedly until I noticed that the touchpad of that computer had its own On/Off switch which I must have been hitting by accident. Notably, the switch did not help to turn it back on. I just became careful not to press it, and before long I took to using an external wireless keyboard with integrated wireless touchpad, and I haven't had that problem since.

UPDATE: (Note: link below broken, solution is above) Since posting this "solution" I posted a comment which apparently met the user's needs. Having only just now learned that the comments remain only temporarily and are automatically deleted, I'm reposting the content of the useful comment below that it may be preserved for others:

I was sharing the "solution" that worked for me. Today it occurred to me to google for solutions more closely fitting your original question and found the following link. It isn't what I would personally consider "convenient", but it could at least be more elegant by making it a script out of it. I found this (see below) – gyropyge Sep 25 at 20:06

Press Alt+F2 and type in gksudo modprobe -r psmouse Type in the password, press Enter, and then press Alt+F2 again for entering the following gksudo modprobe psmouse and then press Enter