A similar question previously posted at Super User is Why does my Windows 7 computer freeze after waking up from Sleep?, but none of the previous answers intially appeared to solve my problem or were the same as my initial answer.
On one of my Windows 7 machines, the mouse would be permanently frozen after the machine woke up from sleep. The mouse would not move though the cursor was displayed. I had no option but to power down the machine and reboot.
This happened often, though not always. If the machine had only been sleeping a few minutes, I could wake it up and use the mouse. If the machine had been sleeping an hour or so, then the mouse would be permanently frozen when the machine woke up.
Best Answer
I initially thought the problem might be caused by the Windows 7 Advanced Power Setting "USB Selective suspend setting" being Enabled, which is apparently the default for Windows 7. This allows Windows to disable USB devices that are infrequently used, so it seemed this might be happening in my case, with a machine that frequently sleeps. This setting can be changed by navigating to:
What I've found through experiment is that my problem is solved by using a newer mouse. Both the new mouse and the old mouse are supposedly identical, and were purchased as the Microsoft Optical Intellimouse. The freeze problem happens repeatably with my older mouse, whether USB selective suspend is enabled or disabled. The freeze problem does not happen with the newer mouse, whether USB selective suspend is enabled or disabled.
In all my tests, both mice have been used directly connected to the PC via the same USB connector. No mousepad was used -- both mice function ok on my desktop without a mousepad. There are no options in the BIOS for my PC to change USB settings for mice. The PC is relatively new, an HP Pavilion Slimline purchased about a year ago.
Remarkably, this answer (replacing with a new, apparently identical mouse) is the same as one of the answers given on the similar question.