VirtualBox Error 0x80040154 – How to Fix When It Won’t Open on Windows 8.1

virtualboxwindowswindows 8.1

VirtualBox won't open.
Here's what the error says:

Failed to create the VirtualBoxClient COM object.
The application will now terminate.

Callee RC: REGDB_E_CLASSNOTREG (0x80040154)

Screenshot:

It all started when I tried to install "Xamarin Android Player" and it installed a separate version of VirtualBox (I was originally on version 5.0.12, it tried installing version 5.0.4), so I tried opening it and it failed. I tried opening VirtualBox and I got that error, and it kept giving me that error through every version I installed (2.2 to 5.0.15) and I'm completely stumped.

My specs:

  • Computer model: Asus TransformerBook T100
  • CPU: 1.88 GHz quad-core Intel Atom CPU
  • RAM: 2 GB of RAM (I don't know what type)
  • Storage: 32 GB SSD with 3 GB remaining before install (424 MB after)
  • Operating system: Windows 8.1 with Bing

What can I do?

Best Answer

You will have to uninstall that Xamarin player AND Virtualbox completely. Then remove all traces of both that may have been left behind (Revo Uninstaller is a good tool for that).
If you have a system-restore point dating from before you attempted to install Xamarin it may be less hassle to go back to that.
Reboot and then FIRST install Xamarin, then VirtualBox.
Oldest version FIRST.

It is possible that that combination doesn't work either. If that is the case you will have to again completely uninstall both and then decide which one you really need and only install that.

Please note: Because you have been trying multiple versions of VirtualBox without cleanly uninstalling any of them it is possible your Windows installation is already damaged to the point it is no longer possible to get back into a clean state. If that is the case you hopefully have a restore point dating from before the time problems started. If not a re-install will be needed...

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