My mouse has recently started a very strange behaviour in that left = up, right = down, up = right and down = left. i.e. it's like my mouse is rotated by 90 degrees. I have tried uninstalling the mouse, run spybot and still no joy. It's rather frustrating and I'm going loopy – literally.
Mouse is rotated by 90 degrees
mouse
Best Answer
Check the mouse settings. There are some mouse drivers that let you change the direction of movement (or rotate the direction of movement). I think this is for use with trackballs.
There is also a program, Sakasa Mouse, that will rotate the mouse movement. The program is intended as a joke so check if someone installed it to mess with you. You shouldn't install it to fix the problem though, because as GwenKillerby states below, it's full of malware.
Barring that, you could turn your monitor 90 degrees the opposite direction and use the computer while lying on your side. ;-)