Linux – Is it possible to run Adobe After Effects (CS6 or later versions) under Wine

Actually, your problem is more likely that /opt/local/bin isn't in your (or root's) $PATH, which will happen if you are using a Terminal window that was open when you installed MacPorts or if you overrode its attempt to add $PATH to your shell configuration. If there are XCode issues, you won't find out about them until you can run port.

EDIT: per comments, this appears to be a missing tclsh. On my Snow Leopard system, its vitals:

mress:10078 Z$ ls -l /usr/bin/tclsh
lrwxr-xr-x  1 root  wheel  8 Nov 19  2009 /usr/bin/tclsh@ -> tclsh8.5
mress:10079 Z$ ls -lL /usr/bin/tclsh
-rwxr-xr-x  1 root  wheel  42640 Jul 23  2009 /usr/bin/tclsh*
mress:10080 Z$ pkgutil --file-info /usr/bin/tclsh
volume: /
path: /usr/bin/tclsh

pkgid: com.apple.pkg.BSD
pkg-version: 10.6.0.1.1.1238328574
install-time: 1258693096
uid: 0
gid: 0
mode: 755

I did some research and found a this thread that claims that the programming languages should work under Wine. Someone on the same thread said he/she ran it in VirtualBox instead of Wine.

However, the Mindstorms software is listed in Wine's application data as being "garbage." I think that means it doesn't run at all.