Windows 7 – How to Turn Off WinHttp Proxy

VPN would create a new network device, you can see it in ifconfig command, and then route all system network to that device, you could see the route use route command.

But HTTP Proxy (in this case, the Charles) is different, it just open a port, to use it, you must specify your application setting to use that port for HTTP stuffs. and as Kevin Reid's answer, curl, wget etc don't read OS X's system wide settings.

If your proxy is SOCKS (Charles supports both HTTP and SOCKS), you could use ProxyChains or tsocks for application doesn't support proxy setting.

e.g.:

$ proxychains git clone https://github.com/rofl0r/proxychains-ng

You need to follow - http://support.microsoft.com/kb/2777643

"How to configure proxy server settings in Windows 8"

What you had posted works fine in previous versions of Windows, you are most likely going to use the section: "How to configure proxy server settings through Web Proxy Auto-Discovery Protocol (WPAD)