Google-chrome – Open current chrome tab with a different profile

There is an extension called OpenHere that will do this. It will add the option in the right click context menu Open in This Window. Just right clcik on the link you want to open in the same tab.

Edit in response to comment:

You can do it with AutoHotkey. You have need to download it and install it on your PC. After that just copy the code below and save it with a .ahk extension.

SetTitleMatchMode, RegEx
#IfWinActive, - Google Chrome$
!RButton::  
    !LButton::  
        KeyWait, Alt  
        Click, Right  
        SendInput, e  
        ControlFocus, Chrome_OmniboxView1  
        SendInput, ^a{Backspace}  
        SendInput, ^v{Enter}   
        return
#IfWinActive

Now when you press Alt + LClick, it will copy the link to the clipboard and past it in the address bar of Chrome. Just press the button and click and release with the click and the link will open in the same tab.

To reset your user profile, shut down Chrome and then open the following directory path:

• On Windows XP: C:\Documents and Settings\Your User Name\Local Settings\Application Data\Google\Chrome\User Data\
• On Windows Vista, 7 or 8: C:\Users\Your User Name\AppData\Local\Google\Chrome\User Data\
• On Mac OS X: ~/Library/Application Support/Google/Chrome/
• On Linux: ~/.config/google-chrome/

Delete the profile you believe is damaged. Most users will simply have a “Default” user profile, which is what you’ll want to delete. Restart Chrome and optionally login to Sync to restore your bookmarks and other goodies.

Further steps to manage the user profile are in the Google Support Forum

EDIT : As your comments below suggest that the answer doesnt solve the problem. So on further research I found out that it is the behavior of chrome browser(version 22.0.1221.0). Find the bug-filed reference here: Issue 139521

EDIT 2 : A related issue is the lack of a "Close Profile" option Issue 130656 which should properly close all windows and background tasks