Since there is already and answer submitted, and a useful and valid one at that, I do not want to distract from its own usefulness but there are indeed points to raise that go way beyond just a short comment. So consider this "augmentation", which is hopefully valid but primarily in addition to what has already been said.

The truth is to really consider "how your application uses the data", and to also be aware of the factors in a "sharded environment" as well as your proposed "container environment" that affect this.

The Background Case

The general take on the practice recommendation for co-locating the mongos process along with the application instance is to obviate any network overhead required in order for the application to communicate with that mongos process. Of course it is also "recommended practice" to specify a number of mongos instances in the application connection string in the case where that "nearest" node should not be available for some reason then another could be selected, albeit with the possible overhead of contacting a remote node.

The "docker" case you mentions seems somewhat arbitrary. While it is true that one of the primary goals of containers ( and before that, something like BSD jails or even chroot ) is generally to achieve some level of "process isolation", there is nothing really wrong with running multiple processes as long as you understand the implications.

In this particular case the mongos is meant to be "lightweight" and run as an "additional function" to the application process in a way that it is pretty much a "paired" part of the application itself. So docker images themselves don't have an "initd" like process but there is not really anything wrong with with running a process controller like supervisord ( for example ) as the main process for the container which then gives you a point of process control over that container as well. This situation of "paired processes" is a reasonable case and also a common enough ask that there is official documentation for it.

If you chose that kind of "paired" operation for deployment, then it does indeed address the primary point of maintaining a mongos instance on the same network connection and indeed "server instance" as the application server itself. It can also be viewed in some way as a case where the "whole container" were to fail then that node in itself would simply be invalid. Not that I would recommend it, and in fact you probably should still configure connections to look for other mongos instances even if these are only accessible over a network connection that increases latency.

Version Specific / Usage Specific

Now that that point is made, the other consideration here comes back to that initial consideration of co-locating the mongos process with the application for network latency purposes. In versions of MongoDB prior to 2.6 and specifically with regard to operations such as with the aggregation framework, then the case there was that there would be a lot more network traffic and subsequent after processing work performed by the mongos process for dealing with data from different shards. That is not so much the case now as a good deal of the processing workload can now be performed on those shards themselves before "distilling" to the "router".

The other case is your application usage patterns itself with regard to the sharding. That means whether the primary workload is in "distributing the writes" across multiple shards, or indeed being a "scatter-gather" approach in consolidating read requests. In those scenarios

Test, Test and then Test Again

So the final point here is really self explanatory, and comes down to the basic consensus of any sane response to your question. This is not a new thing for MongoDB or any other storage solution, but your actual deployment environment needs to be tested on it's "usage patterns" as close to actual reality just as much as any "unit testing" of expected functionality from core components or overall results needs to be tested.

There really is not "definitive" statement to say "configure this way" or "use in this way" that actually makes sense apart from testing what "actually works best" for your application performance and reliability as is expected.

Of course the "best case" will always be to not "crowd" the mongos instances with requests from "many" application server sources. But then to allow them some natural "parity" that can be distributed by the resource workloads available to having at "least" a "pool of resources" that can be selected, and indeed ideally in many cases but obviating the need to induce an additional "network transport overhead".

That is the goal, but ideally you can "lab test" the different perceived configurations in order to come to a "best fit" solution for your eventual deployment solution.

I would also strongly recommend the "free" ( as in beer ) courses available as already mentioned, and no matter what your level of knowledge. I find that various course material sources often offers "hidden gems" to give more insight into things that you may not have considered or otherwise overlooked. The M102 Class as mentioned is constructed and conducted by Adam Commerford for whom I can attest has a high level of knowledge on large scale deployments of MongoDB and other data architectures. Worth the time to at least consider a fresh perspective on what you may think you already know.

The hard connection limit was actually 20,000 but it was removed in version 2.6 and you are now only limited by memory or open file descriptors (whichever you run out of first). That being said, with connections running into the thousands, even if you can manage it you will be using a lot of memory (1MB per connection for the stack).

At that point you start to evaluate other options for mongos deployment. You can have a dedicated set of mongos hosts and take advantage of some of the nice HA options built into the drivers and pass in an list of possible mongos processes to use. If you are concerned about latency, you could potentially collocate (some of) the mongos processes on your shard hosts.

Basically you've started to hit the number of nodes where you are into more advanced design decisions and it really depends on several factors as to what is right for you now, and what is right for you in the future. If you have some money to throw at it, this is perfect fodder for the type of consulting MongoDB offer (disclosure: I was once one of the people delivering such consulting). If not, you are asking the right questions, so keep an eye on resource utilisation and see what makes sense for your deployment as you grow.