MacOS – Error configuring mcrypt after upgrading to El Capitan

It seems there are 2 memcache extensions. There is memcached and memcache the latter one does not seem to be maintained anymore last stable from 2012.

It looks like your code depends on Memcache since you are using brew, you could just do:

brew install php55-memcache

or

pecl install 

Install brew by issuing:

ruby -e "$(curl -fsSL https://raw.githubusercontent.com/Homebrew/install/master/install)"

A quick solution is to use homebrew to install python into /usr/local/bin so that your pip can run against a user-modifiable python framework.

brew install python
pip --version

Disabling System Integrity Protection is also an option, but I don't recommend that for anything but professionally managed and fire walled servers where you have the manpower to manage intrusion detection or if you are a developer/sysadmin and need to test things with and without SIP.

ls -lO /System/Library/Frameworks/Python.framework/Versions/2.7/
csrutil status

You will see that the restricted flag is set which cannot be removed even as root while SIP is engaged.

Using homebrew makes it possible to manage pip and python separately than the system provided version. As a bonus, the homebrew framework is designed to ease maintainance and patch/chores via automation.