MacOS – Can’t force quit frozen iTunes in OS X Yosemite

Go to folder where you store podcast episodes you've subcribed to. (By default it's something like "itunes" folder in "mymusic" folder).

Search for folder named "Downloads". That folder is used for storing temporary files while downloading particulary episode, and it should be empty.

If ITunes crashes, some parts of the episode remain in this folder and that's causing the problem you encountered. If happens that there are some folders or files with .tmp extension, delete them and then try again to download particular episode.

That other answer isn't good because you should not shut down your computer, and it is very unlikely that malware has anything to do with not being able to shut down an application. Do this

• Type sudo killall Google\ Chrome on the Terminal.

• If this does not work, do this:

  pgrep -x "Google Chrome"
  

  You will see a number, then type kill -9 numberhere where numberhere is the number that the pgrep command returned.

And to instatly delete the app, no matter if it is open or not, do:

sudo rm -rf /Applications/Google\ Chrome.app

Then type your password.

The reason you get a permission denied error is because you need root access do to this, just use sudo on the terminal for this.