Assuming the drive inside the My Passport has a SATA connection, then you can just take the drive as-is without any need for re-formatting or changing any data.
However you should look into the specific model of drive you've got — some external drives are manufactured with direct USB interfaces to save costs, rather than a SATA interface with a USB bridge.
- Connect the external drive or device to the Mac
- Reboot the Mac and after the startup chime hold down the OPTION key during boot until you see the boot selection menu
- Click the external volume to boot from it
After this steps, you will find that external drives typically are shown with an orange icon, with their interface printed on the icon itself. Similarly, CD’s and DVD’s are shown with a disc icon. In this screen shot example, the right-most orange boot drive is a USB flash disk.
This works for quite literally any boot volume, whether it’s an external USB drive of any sort, a Thunderbolt hard drive, boot DVD, CD, the Recovery partition, even in dual-boot environments with other versions of OS X, or a Linux or a Windows partition with Boot Camp, if it’s bootable and connected to the Mac it will be visible at this boot manager.
Though boot DVD’s and CD’s will be visible through the aforementioned boot manager, you can also start the Mac directly to DVD or a connected disc by holding down the “D” key during restart after you hear the chime. This is fairly uncommon these days, but it was the primary method of accessing recovery partitions before OS X became a download from the App Store, and before USB installer drives became more common.
Additionally, Macs with recovery partitions can be start directly into Recovery HD by holding down Command+R during system start.
Though recovery and discs can be booted with their own commands, it’s ultimately easier to just remember the Option key method since it is a single key and because it’s universal. The only exception is with target disk mode, which requires a different sequence to use.
Best Answer
Intel Macs can boot to a USB volume, but in this case it will not work. The reason is because the new Mid 2011 macs ship with 10.7, as you mentioned. Macs ship with a minimum supported OS, and will not boot or allow installation of any OS prior to that. Therefore, a Mac that shipped with 10.7 will not boot to a 10.6 install. You'll probably be able to see in when holding option at startup, but if you select it it will likely show an Apple logo and hang there.