Deleting a podcast off of an iPod Touch

With iOS 4, you can make a playlist directly on your device. Go to the Music app, then Playlists, then "Add Playlist...". Type in the name for the playlist, hit Save, and you're presented with a screen to add items to the playlist. Select "Podcasts" (by default, it's found under "More") and select the item you want to play. Tap "Done".

You're all set - just select the item from the playlist and only that item will play.

The podcasts part of iTunes just manage those you have either subscribed to, or subscribed and unsubscribed but still have episodes. It looks like your issue is related to trying to manually manage these, which will let you add the files to your iPod, but iTunes really doesn't know about the structure behind them.

I would recommend having it manage them for you. In that case, you can also tell it to delete those (or keep those) you want after you listen.

For example, I have a couple of concerts from NPR on my iPod that I keep, but my other daily/weekly podcasts delete after they have been listened too.

I expect the reason you are seeing the difference between iTunes and the iPod is the way you are currently mixing the two methods.